Manchester United pair Harry Maguire and Manuel Ugarte are both doubts for the Europa League fixture against Real Sociedad.
Neither player trained on Wednesday morning, and it is unlikely that they will travel out for the game in Spain.
Maguire was replaced in injury time during the penalty shootout defeat to Fulham in the FA Cup at the weekend.
Ugarte, meanwhile, was substituted just 10 minutes after halftime, with Alejandro Garnacho being put on in his place.
